1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity associated with bortezomib, a proteasome inhibitor Employed in the procedure of several myeloma. Its synthesis or research is essential for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the remedy of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise sorts of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their review is significant for optimizing the manufacturing course of action and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to treat breast cancer, and these intermediates are 3 associated with its output.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Utilized in the procedure of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers for instance ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and compact cell lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, that have numerous programs, like antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an CAS NO.827026-45-9 oral drug for style two diabetic issues that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of various gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication employed to manage variety two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).